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In a statement, the Danish drugmaker said that the process of closing down FLOW is already underway, coming after its independent data safety monitoring committee concluded that the results met certain pre-specified criteria for stopping the trial early for efficacy. The large-scale trial started in 2019 and has enrolled 3,534 subjects at hundreds of sites across 28 countries, aiming to show that a once-weekly subcutaneous dose of Ozempic can reduce a compositive primary endpoint covering a battery of kidney outcomes

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