The search methodology included terms as oxidative stress, reactive oxygen species, biomarkers, hypertension, endothelial dysfunction, mitochondrial dysfunction, diabetes, -cell damage, vascular dysfunction, hyperglycemia, insulin resistance, vascular complications, diabetic neuropathies, disease progression, antioxidant therapy, clinical trials, and precision redox medicine
A specific oxidoreductase, previously known as apoptosis-inducing-factor mitochondrial-2 (AIFM2), capable of recycling reduced ubiquinol (Co-enzymeQ 10 H 2 ) from ubiquinone at the expense of NAD(P)H, has been presented as a potential ferroptosis inhibitor due to the fact that its overexpression complements the loss of GPx4 in PFA1 and human fibrosarcoma (Figure 2)
Storage Supplied freeze-dried
Zhu, P., Oe, T
Langworth S, Elinder C, Gthe C-J, Vesterber O (1991) Biological monitoring of environmental and occupational exposure to mercury