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HCV-induced ROS play a significant role in HCV pathogenesis, as Kupffer cell activation contributes to pro-fibrotic cytokine and ROS production, leading to hepatic damage 91,92
If you eat a lot of red meat, your baseline carnitine exposure will be higher and that may affect both need and gut microbial conversion to TMAO
Not human dosing guidance read alongside the PubMed references on /learn
And the 500mg dose per capsule is actually ideal, because it maps cleanly onto the evidence-based dosing protocol: one capsule, three times daily with meals
doi:10.1155/2012/324832 Philp D, Goldstein AL, Kleinman HK
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