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when people reach 40, they produce around 30% less glutathione, and by age 65, that reduction can reach 50% Glutathione is made of 3 different amino acids: cysteine, glycine, and glutamic acid

8 Challenges in clinical application Considering the enumerated benefits of GLP-1RA compared to other glucose-lowering drugs including the reduction in HbA1c and weight reduction benefits alongside decreased risk for hypoglycaemia (122) it is not cost effective if used in combination with another incretin (107)