Carnitine plays a central role in the cellular energy metabolism because it transports long-chain fatty acids from the cytosol to the mitochondria for oxidation and adenosine 5'-triphosphate generation
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This allows them to pass intact to the small intestine, where absorption occurs
When itching does occur, it may reflect a direct hypersensitivity to semaglutide itself, an immune response to the medication vehicle (the solution or coating agents), or a reaction to the injection site or oral formulation