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Personal or family history of medullary thyroid cancer or multiple endocrine neoplasia 2A or 2B
Wegovy is a GLP-1 receptor agonist (once-weekly injection) that produces about 15% body weight loss, while Contrave is an oral pill combining naltrexone and bupropion that typically produces 5-8% loss
While some peptides have relatively favorable safety profiles, proper oversight provides crucial benefits
SURMOUNT-1 reported similar rates across tirzepatide doses [2]
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