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GLP-1 analogues have also been reported to prevent and reverse monocrotaline-induced pulmonary arterial hypertension by suppressing ET-1 and enhancing eNOS/sGC/PKG pathways [40], and to improve hypoxia-induced pulmonary hypertension in mice partly via normalization of reduced ET(B) receptor expression [41]

GLUTATHIONE AS A MAJOR CYTOSOLIC LIGAND FOR Fe(II) Because the cytosolic LIP is essentially present as Fe(II), the physiologic ligands for the cytosolic LIP must have affinity for Fe(II)

Vedolizumab exposure levels and clinical outcomes in ulcerative colitis: determining the potential for dose optimisation

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