In published studies, the fragment has not demonstrated meaningful impact on blood glucose, insulin sensitivity, or IGF-1 concentrations at research-relevant doses
[4] Why Vitamin B12 Can Cause Gastrointestinal Symptoms The mechanisms underlying gastrointestinal side effects from vitamin B12 supplementation are not fully established, but several factors may contribute to stomach discomfort in susceptible individuals
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To be absorbed, the vitamin needs to be attached to a protein called intrinsic factor
If you are considering B12 for energy, tiredness or a diagnosed deficiency, our B12 injections page has the detail, and you can book a free consultation to talk it through first