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There are other important secondary outcomes, including the change in logMAR visual acuity, the development of center-involved diabetic macular edema (CI-DME) and the development of retinopathy, macular edema or vitreous hemorrhage requiring treatment

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Efforts to close the destocking gap were frustrated by a sustained period of high interest rates and persistent inflation, while long-lasting supply chain disruption drove up labor and other costs, increasing expenses and further reducing margins