In one of the new clinical trials, Wharton and other researchers tested a higher-dose version of the drug, 25 milligrams rather than 14 milligrams, which is the highest dose Rybelsus comes in
Since muscle tissue is more metabolically active than adipose tissue (fat), loss of muscle mass leads to a reduced metabolic rate
Cautions for the wider drug class Class-level Approved GLP-1 medicines carry label warnings about pancreas inflammation, gallbladder problems, thyroid tumours seen in rodent studies, and low blood sugar when combined with insulin or sulfonylureas (a diabetes drug group)
By improving insulin sensitivity and reducing excess adipose tissue, GLP-1s may indirectly decrease estrogen-driven inflammation for some patients
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