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These outcomes describe research observations, not clinical performance
thus, the spectrum of GSS mutations and the genotypephenotype association remain unclear
Laboratories occasionally report it separately as active B12 or holotranscobalamin
The advent of newer depigmenting molecules such as pycnogenol, orchid and marine algae extracts, cinnamic acid, soy, aloesin and Boswellia has offered more topical options
It is naturally present in human plasma and was isolated by Loren Pickart in 1973
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