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Interestingly, the treatment demonstrated dose-dependent therapeutic effects, with moderate dosages proving more effective than high doses (1,000 mg/kg), possibly due to pharmacodynamic principles, where excessive concentrations saturate biological pathways and diminish therapeutic outcomes (Tyagi et al., 2025
Abstract Obesity and Type 2 diabetes represent global health challenges, and there is an unmet need for long-lasting and effective pharmacotherapies
Identification of the metabolic differences between microbial pathogens and their hosts, as well as the design of species-specific antimicrobial agents targeting the differential metabolic pathways, therefore represent the most promising fields of research and are strongly supported by recent developments in biological methodology and system biology that allow a better understanding of pathogenic mechanisms at various levels [8, 22, 59]
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