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They have been shown to defend dermal fibroblasts from the pro-inflammatory cytokine prostaglandin E2 responsible for suppressing production of collagen and enhancing its degradation

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The MAT1A gene encodes the MAT I (called the alpha form) isoform of methionine adenosyltransferase which is involved in the synthesis of S-adenosylmethionine (SAM or AdoMet)

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