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A peer-reviewed study published in JMIR Formative Research in 2025 found that active subscribers on Second Natures GLP-1-supported programme lost an average of 19.1% of their body weight at 12 months, with 77.7% achieving at least 10% weight loss

Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS

Table 4 also showed that AST and ALT concentrations increased significantly in the CT group, whereas minimal changes in ALT concentration were observed during fasting in the LC group

The primary mechanism of action is the immediate neutralization of reactive oxygen species (ROS) at the cellular level

Unfortunately, in higher amounts, there are limitations to absorption that can lead to significant, although not dangerous, gastrointestinal side effects