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Food Chem 160:148156

The cAMP signaling pathway potentially enhances melanin production and deposition, which serves as a natural defense against UV penetration and facilitates nucleotide excision repair (NER), a crucial process for potentially removing UV-induced DNA lesions and averting mutagenesis

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Tirzepatide's early spikes reflect the Weber effect (elevated reporting in the first 1-2 years post-approval)