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Selective ablation of NTS PPG neurons significantly reduces active GLP-1 levels in both the brain and spinal cord, suggesting that these neurons represent a major source of endogenous central GLP-1 ( In human brain tissue, GLP-1Rs have similarly been confirmed in neurons within the hypothalamus, medulla oblongata, and parietal cortex
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Here, we report a successful desensitization protocol for the first time in two obese diabetic patients with an immediate hypersensitivity to exenatide
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