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This gatekeeping approach means patients with A1C levels between 5.7% and 6.4%the clinical definition of prediabetesfall outside covered indications, even though clinical evidence supports early intervention

The Medicare GLP1 Bridge, manufacturer savings programs, and the arrival of oral options are all expanding access

Colonna, M

Distinct pharmacology: Targets receptors and pathways not fully engaged by CBD or THC

B12 testing is recommended in patients with fatty liver disease who have: Symptoms suggestive of deficiency (anaemia, neuropathy, cognitive changes) Long-term metformin use (MHRA 2022 guidance advises monitoring) Long-term proton pump inhibitor use Vegetarian or vegan diets Conditions affecting absorption (pernicious anaemia, coeliac disease, gastric surgery) Advanced liver disease (NASH, fibrosis, or cirrhosis) Monitoring frequency should be individualised based on disease severity and risk factors