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In the first study, the Authors observed that GLP-1 levels were similar in PCOS and controls in the early phase of the 75-g oral glucose tolerance test (OGTT) until 60 min, but that GLP-1 levels were significantly lower after 180 min, suggesting that women with PCOS might have reduced GLP-1 secretion in the late postprandial phase [45]
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Cagrilintide (AM833) is a long-acting synthetic amylin analog studied as an amylin-receptor agonist for weight management and metabolic disease, most notably in combination with semaglutide (CagriSema)