Key Nutrients Depleted by Corticosteroids Corticosteroids are associated with depletion of multiple nutrients essential for tissue repair, immune defense, and metabolic stability, including: Calcium, vitamin D, magnesium, potassium, zinc, selenium, vitamin C, and protein (1) Mechanisms of Steroid-Induced Nutrient Depletion Calcium & vitamin D: Reduced intestinal absorption and increased urinary loss osteopenia and fracture risk Zinc, selenium & vitamin C: Impaired immune function, delayed wound healing, increased infection risk Protein: Accelerated protein breakdown muscle wasting and connective tissue weakness Magnesium & potassium: Electrolyte imbalance fatigue, weakness, and cardiac rhythm disturbances Why Steroid-Induced Nutrient Depletion Impairs Healing By chronically elevating cortisol signaling, corticosteroids shift the body into a catabolic, stress-dominant state
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Key areas of research: Neuroscience Research Neuroendocrinology Research Melanocortin Receptor Research Behavioral Science Research Hormonal Signaling Research Central Nervous System Research Neurotransmitter Research Reproductive Biology Research Cellular Signaling Research Endocrinology Research References Bremelanotide (PT-141) and Melanocortin Receptor Pharmacology Alpha-MSH Analogs and Melanocortin Signaling Pathways References are provided for research context only and do not constitute medical claims
Graminski GF, Kubo Y, Armstrong RN
