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Animal models show that spontaneous hypertension can be due to reduced GABA inhibition in the part of the hypothalamus that regulates blood pressure

A few report slight increases, possibly related to compensatory responses or anxiety about self-injection

When administered appropriately under medical supervision, side effects may include dehydration, hypocalcemia (low calcium levels), renal impairment, elevated liver enzymes, electrolyte imbalance, and allergic reactions

Up to know, the majority of established and newly synthesized GST inhibitors have been primarily tested for their cytotoxic effect in cancer cell lines and mouse xenograft models, showing promising activities