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Although tretinoin is not considered a spot treatment, applying tretinoin to a pimple can indeed contribute to its reduction in size due to its anti-inflammatory properties and its ability to accelerate cell turnover
Nihon Kyukyu Igakukai Zasshi
Proc Natl Acad Sci U S A 80(7):20772080
Specific neurotrophic effects of HGF were reported on calbindin-D containing hippocampal neurons (Korhonen et al., 2000) and dopaminergic mesencephalic neurons (Hamanoue et al., 1996
However, the results may vary from person to person
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