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Animal studies have shown that it may cause fat to accumulate where it shouldnt, causing liver problems or oxidative stress
Results of a systematic review
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While these polar metabolites are more readily excreted, they nonetheless maintain significant biological properties, contributing to the overall pharmacodynamic profile of flavonoids ( 3.3.4 Excretion The primary excretion pathways for flavonoids and their metabolites include renal (urine) and biliary (bile) routes
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