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The backbone is acylated at the Lysine residue at position 20 with a C20 fatty diacid moiety via a hydrophilic gamma glutamyl linker system
McGuireDKAlexanderJHJohansenOEPerkovicVRosenstockJCooperMEet al
Others require continued refrigeration
But safe does not mean side effect free
What is fascinating is that their effects are not limited to alcohol: preclinical and correlational data indicate possible benefits in decreasing use of nicotine and opioids, which makes sense as alcohol, cannabis, opioid, and nicotine use disorders cluster together genetically into one brain disorder
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