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But it is meaningful that retatrutide was specifically included and showed consistent results with the rest of the GLP-1 class on alcohol-related outcomes

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The increase of ROS within a high oxidative stress level (by decreasing of the antioxidant GPx enzyme) increases the possibility of lipid oxidation, especially LDL-cholesterol and thus favors the formation of anti-LDL-oxidized cholesterol antibodies, which will lead to the initiation of an immune and vascular aggression process (13-18)

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