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Samples were then analyzed by high-performance liquid chromatography/mass spectrometry in order to determine drug concentrations and calculate negative controls samples containing no liver microsomes [2]

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The ratio of fat-mass loss to lean-mass loss was similar to that reported in lifestyle-based intervention in the Look AHEAD trial (241) and surgical treatment for obesity (242)

A thorough baseline evaluationincluding metabolic labs, kidney function, and medical historyensures safe selection and dosing

GLP-1 agonists reduce appetite, slow gastric emptying, and improve glycemic control through glucose-dependent insulin secretion