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(2022) 378:e072117

M.MaihoferA

The estimated oral dose range from animal research is approximately 18 mg/kg, but human pharmacokinetic parameters including bioavailability fraction, Tmax, and clearance remain entirely unknown

According to the joint ATS/ERS/JRS/ALAT 2011 guidelines, HRCT is an essential component of the diagnostic pathway in IPF which can identify UIP by the presence of: [3] Reticular opacities, often associated with traction bronchiectasis Honeycombing manifested as cluster cystic airspaces, typically of comparable diameters (310 mm (0.120.39 in)) but occasionally large