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Gurjar AA, Kushwaha S, Chattopadhyay S, Das N, Pal S, China SP, et al

A 2017 review of 33 trials found that orlistat slightly reduced cholesterol and triglyceride levels, but the reductions were more consistent in people who lost more weight and took orlistat for a shorter time (9)

Studies on the parent compound suggest effects on telomere maintenance, melatonin synthesis enzymes, and markers of cellular senescence (p16, p21, SA--galactosidase)

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