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investigated the warm and cold types of AIHA (wAIHA and cAIHA, respectively) and demonstrated that eryptosis is predominantly driven by cold IgM and/or IgA antibodies rather than warm IgG autoantibodies, as shown by increased PS exposure in response to autoantibodies [329]

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5 CRM: Potential epigenetic therapies for aging-related diseases CR provides an excellent opportunity to prevent aging-related diseases in humans by affecting epigenetic anti-aging

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4 Inflammasome-mediated liver injury: DAMPs released from stressed hepatocytes, damaged mitochondria, and necrotic liver cells activate inflammasome sensors, triggering the oligomerization and activation of inflammasome components

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