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No rapid fat loss yetsignificant fat reduction occurs over several months
Minimal Sensation Most clients report only a brief pinch with no significant discomfort
Considering the widespread expression of GLP-1 receptors in the brain, the authors recommend that future studies should focus on identifying the key neurocircuits involved in mediating the effects of GLP-1 receptor agonists on substance use disorder, as well as determine the specific patient subtypes who are most likely to benefit from these treatments
We now know that the function of at least some of these peptides may be mediated by the modulation of hypothalamic metabolic sensors
Despite these potential risks, discontinuation rates due to the adverse impacts remain low, highlighting the tolerability and effectiveness of GLP-1 agonists for most clients
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