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In diabetes and obesity, growth factor-associated signaling in the brain deteriorates and energy use in the cerebral cortex decreases simultaneously with pro-inflammatory changes, while GLP-1RAs improve neuronal growth and repair, reduce inflammation and apoptosis, as well as oxidative stress [31]

Nanotargeted delivery of immune therapeutics in type 1 diabetes

A Reuters report (Aug 2025) interviewed multiple US doctors on GLP-1s: insurance coverage has tightened in 2025 as many employers drop it for the expensive GLP-1 drugs, said one physician ( [26] )

I will link to those so you can take a deeper dive on the whys of HRT And why we're often starting the estrogen progesterone is because that's laying the groundwork for the improved insulin sensitivity

Foods are also natural sources of glutathione