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SQOR catalyzes the first and rate-limiting step in mitochondrial H 2 S oxidation by transferring electrons from sulfide to ubiquinone (CoQ 10 ), forming ubiquinol (CoQ 10 H 2 ) and a persulfide intermediate, which is further metabolized by downstream enzymes in the sulfide oxidation pathway 46,47

Researchers have studied its effects on tissue repair, angiogenesis, and nitric oxide signaling in preclinical models for more than two decades