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Cancer cells must maintain metabolic homeostasis in a wide range of conditions, including harsh microenvironments in which cancer cells must continue to meet the high bio-energetic demand in order to undergo replication 1

For individuals managing type 2 diabetes, Semaglutide is often combined with other diabetes medications such as metformin, SGLT2 inhibitors, or insulin, depending on the patients needs and medical history

This is akin to the difference between receiving an IV drip and a single injection, with the added benefit of convenience and comfort

Beyond central nervous system actions, the weight-loss effects of GLP-1 analogs also involve peripheral metabolic adaptations

Analyses after randomization were exploratory and cannot confirm causation, and the authors noted that the predominantly White, male population may limit generalizability