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The Bottom Line GLP-1 medications themselves dont cause melasma, but hormonal shifts, inflammation, lifestyle changes, and sun exposure during weight loss can influence pigmentation

doi: 10.1016/j.freeradbiomed.2018.02.009 112 WillisBCLieblerJMLuby-PhelpsKNicholsonAGCrandallEDDu BoisRMet al

There were two other dual agonists whose sequence has been reported so far, Tyr 1 has been used in MAR709 (designed by Finan et al in 2013, described by numerous other names: DA5-CH, DA-JC1, NNC0090-2746, RG7697, etc.) and His 1 has been used in CY-5 (Figure 3)

Adiponectin has also been observed to inhibit TNF- production, which might be an important target for treating obesity-related asthma [29]

This makes it suitable for people with sensitive skin or inflammatory skin conditions such as eczema or rosacea