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What Are Alternative Options

Patients on Tirzepatide 15 mg weekly lost an average of 20.9% or 48.6 lb of their body weight after 72 weeks in the Zepbound Study 1 (NCT04184622) compared to placebo patients who lost an average of 3.1% or 7.2 lb

Furthermore, the complex pharmacokinetics of GLP-1RAs, with uncertain timelines for gastric emptying normalization, necessitates further investigation to establish optimal drug withholding periods before endoscopies.

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But rather than cooling the space, it fueled a larger conversation about access, affordability, and pharmaceutical gatekeeping