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Retatrutide remains one of the most potent options in the emerging class of multi-receptor agonists

The cautionary half is that absolute lean mass still dropped by several pounds in some arms during aggressive weight loss

The medication occupies both receptors simultaneously to suppress appetite and regulate blood glucose levels

4 Preclinical studies of GLP-1 RAs have shown promising antitumor activity in breast cancer, though it is unclear whether these effects are direct or indirect via energy restriction