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This inflammatory response exacerbates the neuronal damage and promotes chronic neuroinflammation (Marusich et al., 2022)
For states of systemic inflammation that involve cells of the peripheral immune system, while for neurodegenerative and neuroinflammatory diseases such as AD, PD, and MS, penetration of the CNS is necessary (Lin et al., 2024
These interactions can affect the efficacy of the medications or increase the risk of side effects
Current options and future directions for NAFLD and NASH treatment
NPs-exposed mice documented down-regulation of cholesterol transport genes, ABCA1 and ABCG1, and upregulation of fatty acid transport gene CD36 in the liver and increased hepatic oxidative stress, underscoring the oxidative stress-associated impairment of cholesterol transport and efflux
