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Patients with certain GLP1R rs6923761 genotypes may experience more pronounced nausea during early titration, allowing your provider to recommend slower dose escalation or prophylactic anti-nausea support upfront

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Retatrutide simultaneously activates GLP-1, GIP and glucagon receptors, allowing researchers to investigate multiple biological pathways using a single peptide compound

doi: 10.1016/j.ajpath.2019.07.011 48 NankiTShimaokaTHayashidaKTaniguchiKYoneharaSMiyasakaN

Davinelli, S., Nielsen, M