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On treatment with a bolus of H 2 O 2 (500 M) to induce oxidative stress, the ratiometric imaging of HeLa cells revealed a decrease in the GSH level from 5.0 to 4.1 mM within 90 s (Fig
For example, the silent information regulator 1 (SIRT1), a NAD + -dependent protein deacetylase, functions as a key upstream regulator for LKB1/AMPK signaling in the liver 50
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