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(2022) observed the activation of the phosphatidylinositol 3-kinase (PI3K)-Akt pathway in mouse liver upon gavage of A
One-week treatment of DIO mice with G49 induces a transient lipid overload in the liver, increases ketogenesis and FGF21 levels Due to the rapid increase (16 h) in circulating FFAs in G49-treated mice (Fig
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Separate trials have also explored its use specifically in people with type 2 diabetes