CrossRef A Higher Risk of Liver Cancer in Alcoholic Fatty Liver Disease than in Non-Alcoholic Fatty Liver Disease: an Analysis of the TriNetX Dabatase Ling-Hui Chang, Sheng-You Su, Chun Lee, Chao-Yu Hsu Journal of Gastrointestinal Cancer .2025;[Epub] CrossRef Letter: Safety and Tolerability of Injectable ExtendedRelease Naltrexone for the Management of Alcohol Use Disorder in Advanced AlcoholAssociated Liver DiseaseAuthors' Reply Luis Antonio Daz, Rohit Loomba Alimentary Pharmacology & Therapeutics .2025
Semaglutide GLP-1 receptor agonist FDA-approved specifically for weight loss Strong appetite suppression Extensively studied with proven results Tirzepatide Dual GLP-1 + GIP agonist Often produces greater total weight loss May offer additional benefits for insulin resistance Currently FDA-approved for diabetes (weight loss approval pending) Our team will help you understand which option is best suited to your body, your metabolism, and your goals
STEP 4 The Stopping Evidence The STEP 4 trial is perhaps the most clinically important study for understanding duration
Nat Rev Microbiol 17:141155
Increased Insulin Secretion GLP-1 receptor agonists promote insulin secretion in a glucose-dependent manner, stimulating the pancreas to release insulin primarily when blood glucose levels are elevated