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However, response may vary: Higher baseline weight Individuals starting at higher body weights may experience: Slower percentage weight loss initially Need for full maintenance doses to achieve optimal effects Potentially better tolerance of higher doses Lower baseline weight Those with lower starting weights might: Achieve therapeutic goals at submaximal doses (e.g., 2.4 mg vs
Within the SELECT population with BMI 30 kg m 2 or 27 kg m 2 with at least one obesity-related comorbidity, the mean weight loss was 14.9% at week 68, compared with 2.4% with placebo 14
Frontiers in Pharmacology , 12
Precisely because of the activation of melanin, it was assumed that naturally increased pigmentation could be a protection against ultraviolet rays and cancer
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