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Obesity is a chronic condition, and patients may benefit from taking GLP-1s long term, especially if they also have conditions such as diabetes, cardiovascular disease, obstructive sleep apnea, or metabolic dysfunction-associated steatohepatitis (MASH)

L., Rodrguez, T

Drinking on semaglutide can intensify nausea, worsen dehydration, slow weight loss progress, and increase the risk of hypoglycemia

SASP (Senescence-Associated Secretory Phenotype) signaling begins declining as the source cells are eliminated Weeks 2-6: Tissue microenvironments improve as SASP-driven inflammation decreases

doi:10.1016/S0140-6736(14)61682-2