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Cardiovascular effects of GLP-1 RAs have been of great interest since the burden from cardiovascular diseases (CVD) has been unbearably increasing in a diabetic population worldwide, despite strict glycemic control and advanced therapeutic techniques to treat CVD

Schieber and Chandel, 2014)

Loss of muscle can be detrimental to metabolism and aging, affecting strength, mobility, decreasing metabolic rate, increasing risk of insulin resistance, diabetes, cardiovascular health, and overall quality of life

Liver, spleen, and pancreas are often affected

Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragmentsthe importance of immunofocusing in subunit vaccine design