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It was also an early observation that a higher dose of GLP-1 is needed to produce satiety and reduced food intake than to the antidiabetic effect, so a low dose GLP-1 analog could be used to study weight loss independent effects of GLP-1
Unlike insulin or other non discretionary drugs, there is a wide gap between the eligible population and the number of people actually on therapy
Di Biase S, Lee C, Brandhorst S et al (2016) Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity
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