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This study was supported by the Special Coordination Funds for Promoting Science and Technology, Creation of Innovation Centers for Advanced Interdisciplinary Research Areas (Innovative Bioproduction Kobe), MEXT, Japan

It is possible that semaglutide interferes with vascular healthy and blood flow resulting in an ischemic event restricting blood flow to the optic nerve

Peripheral administration of PYY 3-36 reduces caloric intake, increases postprandial insulin levels, and enhances insulin sensitivity, thermogenesis, lipolysis, and fat oxidation in both lean and obese humans as well as in nonhuman primates 36,37,38,39,40