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While neither cagrilintide nor retatrutide has been studied exclusively in male populations, available trial data include substantial numbers of male participants

The safety profile of BPC-157 in published research is notable for the absence of reported adverse effects across a wide range of doses

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Some patients may benefit from transitioning to lower doses of GLP-1 medications rather than complete discontinuation, though this approach requires further research to establish optimal dosing strategies

Stratification according to history of CVD prior to index revealed reduced HRs for prostate cancer with GLP-1RA vs basal insulin use among men with CVD in both the ITT analysis (HR 0.75