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Older men with comorbidities should start at lower initiation doses
The alternative pathway for LTA 4 metabolism is prominent in cells expressing the enzyme LTC 4 synthase (LTC4S or glutathione- S -transferase), which is found on the nuclear envelope of cells and adds the tripeptide glutathione (glutamyl-cysteinyl glycine) to carbon-6 to yield peptido-leukotriene C 4 (LTC 4 , 5 S ,6 R - S -glutathionyl-7,9,11,14-( E,E,Z,Z )-eicosatetraenoic acid), the first of the 'cysteinyl leukotrienes'
Prognosis and Recovery The outlook for melena patients depends on the cause and treatment
The key difference is in the specific formulations and their stability profiles, which vary by manufacturer and preparation method
(2017) 12:CD006095
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