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2013 Nov;10(11):2790-7

DNA dot-blot analysis also in line with activity assay, which showed an increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels (Fig

Its only completed human trial (for post-operative ileus) did not meet its primary endpoint, and development was discontinued

These findings similarly indicated that SFN and CDDO effectively reversed the expression levels of Nrf2 and NQO1 proteins, suggesting that HT-induced ferroptosis in colorectal cancer is linked to the suppression of the Nrf2 signaling pathway

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