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(Jourdan et al., 2020)

More severe but uncommon effects include pancreatitis or thyroid tumors (seen in animal studies)

Biotechnol Annu Rev

When combined with a reduced-calorie diet and increased physical activity, clinical trials (primarily the STEP 1 trial in adults without diabetes) have shown that Wegovy can help patients lose an average of 1215% of their body weight over 68 weeks, though individual results vary