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Huang et al

Its rooted in real neurological changes that come with perimenopause and midlife

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These molecules were tested for DPP-4 inhibitory activity, with 6-methyl-5-(4-methylpyridin-2-yl)-1-phenyl-1H-pyrazolo[3,4-d] pyrimidin-4(5H)-one (compound 29) (Figure 5) showing the highest activity (IC 50 = 1.06 M)

The agency had already referred the issue to the public prosecutor back in April